Data-Driven Retrospective Correction of B₁ Field Inhomogeneity in Fast Macromolecular Proton Fraction and R₁ Mapping.

ABSTRACT: Correction of B₁ field non-uniformity is critical for many quantitative MRI methods including variable flip angle (VFA) T₁ mapping and single-point macromolecular proton fraction (MPF) mapping. The latter method showed promising results as a fast and robust quantitative myelin imaging approach and involves VFA-based R₁=1/T₁ map reconstruction as an intermediate processing step. The need for B₁ correction restricts applications of the above methods, since B₁ mapping sequences increase the examination time and are not commonly available in clinics. A new algorithm was developed to enable retrospective data-driven simultaneous B₁ correction in VFA R₁ and single-point MPF mapping. The principle of the algor

SUBMITTER: Yarnykh VL 

PROVIDER: S-EPMC8711232 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature