Patient-reported Outcomes in Chinese Subjects Treated with OnabotulinumtoxinA for Crow's Feet Lines.

ABSTRACT:

Background

Crow's feet lines (CFLs) can impact the emotional state, self-perception, and consciousness regarding appearance of patients.

Objective

This study sought to assess patient-reported outcomes after onabotulinumtoxinA treatment for CFLs among Chinese subjects.

Methods

A five-month, double-blind, randomized, parallel-group, placebo-controlled Phase III clinical study was conducted including Chinese adults with moderate-to-severe CFLs at maximum smile. Subjects were randomized 3:1 to 24 U of onabotulinumtoxinA or placebo and completed the 11-item Facial Line Outcomes (FLO-11) questionnaire and Facial Line Satisfaction Questionnaire (FLSQ) at baseline; on Days 8, 15, and 30; and monthly thereafter until Day 150. Item-level and/or domain analyses for the FLO-11 an

SUBMITTER: Wu Y 

PROVIDER: S-EPMC8711615 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature