Genetic risk assessment for hereditary renal cell carcinoma: Clinical consensus statement.

ABSTRACT:

Background

Although renal cell carcinoma (RCC) is believed to have a strong hereditary component, there is a paucity of published guidelines for genetic risk assessment. A panel of experts was convened to gauge current opinions.

Methods

A North American multidisciplinary panel with expertise in hereditary RCC, including urologists, medical oncologists, clinical geneticists, genetic counselors, and patient advocates, was convened. Before the summit, a modified Delphi methodology was used to generate, review, and curate a set of consensus questions regarding RCC genetic risk assessment. Uniform consensus was defined as ≥85% agreement on particular questions.

Results

Thirty-three panelists, including urologists (n = 13), medical oncologists (n = 12), genetic counselors a

SUBMITTER: Bratslavsky G 

PROVIDER: S-EPMC8711633 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature