Surgery-Associated Infections among Infants Born Extremely Preterm.

ABSTRACT:

Objective

To assess the burden of invasive infection following surgery (surgery-associated infections [SAI]) among infants born extremely premature.

Study design

This was an observational, prospective study of infants born at gestational age 22-28 weeks hospitalized for >3 days, between April 1, 2011, to March 31, 2015, in academic centers of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. SAI was defined by culture-confirmed bacteremia, fungemia, or meningitis ≤14 days following a surgical procedure.

Results

Of 6573 infants, 1154 (18%) who underwent surgery were of lower gestational age (mean [SD]: 25.5 [1.6] vs 26.2 [1.6], P < .001), lower birth weight (803 [220] vs 886 [244], P < .001), and more likely

SUBMITTER: Shane AL 

PROVIDER: S-EPMC8712381 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature