Incidence and Predictors of Heart Failure in Patients With Atrial Fibrillation.

ABSTRACT:

Background

Heart failure (HF) is a frequent cause of hospitalization and death in patients with atrial fibrillation (AF). Identifying AF patients at risk of HF hospitalization could help select individuals for intensive follow-up and treatment.

Methods

We pooled data from 3 randomized trials (ACTIVE-A, RE-LY, AVERROES) of AF patients, for derivation and internal validation of a risk score for first HF hospitalization. Secondary endpoints were cardiovascular death and a composite of HF hospitalizations and cardiovascular death.

Results

In 23,503 patients, the mean age was 71.3 years, and 62% were male. Over a mean follow-up of 2.0 years, 875 patients (3.7%) experienced their first HF hospitalization, and 1037 patients (4.4%) died from cardiovascular causes. Incidence r

SUBMITTER: Krisai P 

PROVIDER: S-EPMC8712577 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature