Regional left ventricular systolic dysfunction associated with critical illness: incidence and effect on outcome.

ABSTRACT:

Aims

Left ventricular (LV) dysfunction can be triggered by non-cardiac disease, such as sepsis, hypoxia, major haemorrhage, or severe stress (Takotsubo syndrome), but its clinical importance is not established. In this study, we evaluate the incidence and impact on mortality of LV dysfunction associated with critical illness.

Methods and results

In this single-centre, observational study, consecutive patients underwent an echocardiographic examination within 24 h of intensive care unit (ICU) admission. LV systolic dysfunction was defined as an ejection fraction (EF) < 50% and/or regional wall motion abnormalities (RWMA). A cardiologist assessed patients with LV dysfunction for the presence of an acute or chronic cardiac disease, and coronary angiography was performed in high

SUBMITTER: Cavefors O 

PROVIDER: S-EPMC8712834 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature