Ontology highlight
ABSTRACT:
SUBMITTER: Li R
PROVIDER: S-EPMC8712858 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Li Rui R Walsh Patrick P Truong Vincent V Petersen Ashley A Dutton James R JR Hubel Allison A
Frontiers in cell and developmental biology 20211214
Differentiation of human induced pluripotent stem cells (hiPSCs) generates cell phenotypes valuable for cell therapy and personalized medicine. Successful translation of these hiPSC-derived therapeutic products will rely upon effective cryopreservation at multiple stages of the manufacturing cycle. From the perspective of cryobiology, we attempted to understand how the challenge of cryopreservation evolves between cell phenotypes along an hiPSC-to-sensory neuron differentiation trajectory. Cells ...[more]