Left ventricular dimensions and cardiovascular outcomes in systolic heart failure: the WARCEF trial.

ABSTRACT:

Aims

There is limited information on the association between left ventricular (LV) dimensions and cardiovascular (CV) outcomes in patients with heart failure (HF) with reduced LV ejection fraction (HFrEF) receiving recommended HF treatment. We investigated the association between LV dimensions and CV outcomes in HFrEF patients receiving recommended HF treatment.

Methods and results

We investigated the association between LV echocardiographic dimensions and CV outcomes using conventional Cox models in 1138 HFrEF patients in sinus rhythm randomized to warfarin or aspirin treatment in the Warfarin vs. Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) trial. LV enlargement, whether by diameter [LV end-diastolic diameter index (LVEDDI) and LV end-systolic diameter index (LVES

SUBMITTER: Ito K 

PROVIDER: S-EPMC8712869 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature