Mortality risk in chronic Chagas cardiomyopathy: a systematic review and meta-analysis.

ABSTRACT:

Aims

This study aimed to estimate the annual mortality risk and its determinants in chronic Chagas cardiomyopathy.

Methods and results

We conducted a systematic search in MEDLINE, Web of Science Core Collection, Embase, Cochrane Library, and LILACS. Longitudinal studies published between 1 January 1946 and 24 October 2018 were included. A random-effects meta-analysis using the death rate over the mean follow-up period in years was used to obtain pooled estimated annual mortality rates. Main outcomes were defined as all-cause mortality, including cardiovascular, non-cardiovascular, heart failure, stroke, and sudden cardiac deaths. A total of 5005 studies were screened for eligibility. A total of 52 longitudinal studies for chronic Chagas cardiomyopathy including 9569 patients

SUBMITTER: Chadalawada S 

PROVIDER: S-EPMC8712892 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature