Blood loss after coronary artery bypass by aspirin responsiveness assessed with preoperative VerifyNow aspirin testing.

ABSTRACT:

Background

Aspirin is important for preventing thrombotic events but also increases bleeding complications. Minimizing bleeding while preventing thrombotic events remains challenging in patients undergoing coronary artery bypass grafting (CABG). Establishing the patient's preoperative aspirin response could distinguish patients at risk for perioperative blood loss.

Objective

Aim was to compare 12-h blood loss after CABG between aspirin-sensitive and aspirin-resistant patients.

Patients/methods

The primary analysis of this substudy of the POPular CABG trial (NCT02352402) included patients that used aspirin monotherapy preoperatively. A preoperative platelet function test by the VerifyNow aspirin assay was performed before CABG and patients were classified as aspirin-se

SUBMITTER: Willemsen LM 

PROVIDER: S-EPMC8713006 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature