Predictive value of using plasma long non-coding RNAs ANRIL and HOXA11-AS for in-stent restenosis.

ABSTRACT: In-stent restenosis (ISR) can pose serious challenges for cardiologists following coronary stent implantation. Early identification of patients at high risk of ISR is considered to be effective for its prevention. However, factors that can reliably predict the risk of ISR remain elusive at present. The present study aimed to investigate the possible association between plasma long non-coding RNA (lncRNA) levels and ISR. A total of 410 patients with single-vessel lesion who received drug-eluting stents (DES) were included in the present study. After 12-36 months of follow-up, coronary angiography was performed and ISR was defined as >50% diameter stenosis at follow-up. RT-qPCR was used to measure lncRNA expression. Expression of the lncRNA RNA antisense non-coding RNA at the INK4 locus (ANR

SUBMITTER: Jin Z 

PROVIDER: S-EPMC8713178 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature