Early-Life Environmental Exposures and Blood Pressure in Children.

ABSTRACT:

Background

Growing evidence exists about the fetal and environmental origins of hypertension, but mainly limited to single-exposure studies. The exposome has been proposed as a more holistic approach by studying many exposures simultaneously.

Objectives

This study aims to evaluate the association between a wide range of prenatal and postnatal exposures and blood pressure (BP) in children.

Methods

Systolic and diastolic BP were measured among 1,277 children from the European HELIX (Human Early-Life Exposome) cohort aged 6 to 11 years. Prenatal (n = 89) and postnatal (n = 128) exposures include air pollution, built environment, meteorology, natural spaces, traffic, noise, chemicals, and lifestyles. Two methods adjusted for confounders were applied: an exposome-wide asso

SUBMITTER: Warembourg C 

PROVIDER: S-EPMC8713646 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature