Age at menarche, age at menopause, reproductive years and risk of fatal stroke occurrence among Chinese women: the Guangzhou Biobank Cohort Study.

ABSTRACT:

Background

The relationship between women's reproductive characteristics and stroke events is unclear. We aimed to investigate age at menarche, age at menopause and number of reproductive years in relation to fatal stroke occurrence in the Guangzhou Biobank Cohort Study.

Methods

In total, 16,504 postmenopausal women without stroke, heart disease or a cancer history at baseline were included and followed up for a median of 12.0 years. After review of available records, 222 stroke deaths were recorded. Cox proportional hazards regression was used to assess the associations between the risk of fatal stroke occurrence and age at menarche, age at menopause and number of reproductive years.

Results

In the whole cohort, compared with those aged 15 years at menarche, an incre

SUBMITTER: Hu ZB 

PROVIDER: S-EPMC8714414 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature