Systematic review and meta-analysis of cervical metastases in oral maxillary squamous cell carcinoma.

ABSTRACT:

Background

Management of the node-negative neck in oral maxillary squamous cell carcinoma (SCC), encompassing the hard palate and upper alveolar subsites of the oral cavity, is controversial, with no clear international consensus or recommendation regarding elective neck dissection in the absence of cervical metastases.

Aim

To assess the occult metastatic rate in patients with clinically node negative oral maxillary SCC; both as an overall metastatic rate, and a comparison of patients managed with an elective neck dissection at index surgery, compared to excision of the primary with clinical observation of the neck.

Methods and results

A systematic review was performed by two independent investigators for studies relating to oral maxillary SCC and analysed according t

SUBMITTER: Chia C 

PROVIDER: S-EPMC8714539 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature