Sunlight exposure in infancy decreases risk of sporadic retinoblastoma, extent of intraocular disease.

ABSTRACT:

Background

Prior ecologic studies suggest that UV exposure through sunlight to the retina might contribute to increased retinoblastoma incidence.

Aims

Our study objectives were (1) to examine the relationship between exposure to sunlight during postnatal retinal development (prior to diagnosis of sporadic disease) and the risk of retinoblastoma, and (2) to examine the relationship between sun exposure during postnatal retinal development, and the extent of disease among children with unilateral and bilateral retinoblastoma.

Methods and results

We interviewed 511 mothers in the EpiRbMx case-control study about their child's exposure to sunlight during postnatal retinal cell division by examining three time periods prior to Rtb diagnosis coinciding with developmental st

SUBMITTER: Orjuela-Grimm M 

PROVIDER: S-EPMC8714544 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature