Ketamine for the treatment of mental health and substance use disorders: comprehensive systematic review.

ABSTRACT:

Background

In the past two decades, subanaesthetic doses of ketamine have been demonstrated to have rapid and sustained antidepressant effects, and accumulating research has demonstrated ketamine's therapeutic effects for a range of psychiatric conditions.

Aims

In light of these findings surrounding ketamine's psychotherapeutic potential, we systematically review the extant evidence on ketamine's effects in treating mental health disorders.

Method

The systematic review protocol was registered in PROSPERO (identifier CRD42019130636). Human studies investigating the therapeutic effects of ketamine in the treatment of mental health disorders were included. Because of the extensive research in depression, bipolar disorder and suicidal ideation, only systematic reviews and

SUBMITTER: Walsh Z 

PROVIDER: S-EPMC8715255 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature