Hereditary angioedema due to C1 inhibitor deficiency: real-world experience from the Icatibant Outcome Survey in Spain.

ABSTRACT:

Background

The Icatibant Outcome Survey (IOS) is an international registry monitoring the use of icatibant, a bradykinin B₂ receptor antagonist indicated for the acute treatment of hereditary angioedema (HAE) attacks. Our goal was to assess disease characteristics and icatibant treatment outcomes in patients with HAE due to C1 inhibitor deficiency (HAE type 1 or 2 (HAE-1/2)) from Spain relative to other countries participating in IOS.

Methods

Descriptive retrospective analyses of data are reported from 10 centers in Spain vs 51 centers in 12 other participating countries (July 2009 to January 2019).

Results

No meaningful differences were identified between patients in Spain (n = 119) and patients across other countries (n = 907) regarding median age at symp

SUBMITTER: Guilarte M 

PROVIDER: S-EPMC8715569 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature