Serum Uric Acid and Risk of Chronic Heart Failure: A Systematic Review and Meta-Analysis.

ABSTRACT: Objectives: A systematic review and meta-analysis was performed to evaluate the potential prognostic role of serum uric acid (SUA) in patients with chronic heart failure (CHF). Methods: The Embase, PubMed, Web of Science and Cochrane Library databases were searched up to 5 April 2021 for relevant publications. Random effects model was used to pool data. STATA15.0 software was used to perform meta-analysis. Heterogeneity was assessed using the Cochran Q statistic (significance level of P < 0.10) and I ² statistics (significance level of 50%). Results: Ultimately, 18 publications reporting adverse events in CHF patients were included. The results indicate reveal associations between a high level of SUA and the risk of all-cause mortality (HR 2.24

SUBMITTER: Miao L 

PROVIDER: S-EPMC8715937 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature