Synthesis, characterization, antioxidant, antileishmanial, anticancer, DNA and theoretical SARS-CoV-2 interaction studies of copper(II) carboxylate complexes.

ABSTRACT: Copper(II) carboxylate complexes [Cu₂(OOCR)₄L₂] (1) and [Cu₂(OOCR`)<sub>4</sub>OCO(R`)CuL₂]_n (2), where L = 2-methyl pyridine, R = 2-chlorophenyl acetate and R` = 2-fluorophenyl acetate were synthesized and characterized by FT-IR spectroscopy and single crystal X-ray analysis. Complex 1 exhibits the typical paddlewheel array of a dinuclear copper(II) complex with carboxylate ligands. In complex 2, this scaffold is further extended into a polymeric arrangement based on alternate paddlewheel and square planar moieties with distinct coordination spheres. The complexes showed better 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical scavenging activities and have been found to be

SUBMITTER: Viola 

PROVIDER: S-EPMC8716173 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature