Temporal Validation of a Predictive Score for Death in Children with Visceral Leishmaniasis.

ABSTRACT:

Objectives

To perform a temporal validation of a predictive model for death in children with visceral leishmaniasis (VL).

Methods

A temporal validation of a children-exclusive predictive model of death due to VL (Sampaio et al. 2010 model), using a retrospective cohort, hereby called validation cohort. The validation cohort convenience sample was made of 156 patients less than 15 years old hospitalized between 2008 and 2018 with VL. Patients included in the Sampaio et al. 2010 study are here denominated derivation cohort, which was composed of 546 patients hospitalized in the same hospital setting in the period from 1996 to 2006. The calibration and discriminative capacity of the model to predict death by VL in the validation cohort were then assessed through the procedure o

SUBMITTER: Foinquinos J 

PROVIDER: S-EPMC8716242 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature