Reductive Effect of Acitretin on Blood Glucose Levels in Chinese Patients With Psoriasis.

ABSTRACT: Background: Psoriasis is a skin condition associated with increased risks of developing metabolic diseases, such as diabetes and hyperlipidaemia. Retinoid drugs, including acitretin, are commonly used to treat psoriasis due to its low cost and tolerable side effects. Objective: This study aimed to explore the influence of acitretin on patients' metabolism levels, especially lipid and glucose. Methods: In this retrospective study, a total of 685 psoriatic patients and 395 age/sex matched controls were enrolled. The demographic and biochemical indexes of each participant were recorded. Acitretin (30 mg/d) combined with the topical ointment calcipotriol was used to treat the psoriatic patients, and the glucose and lipid profiles of patients before and after acitretin trea

SUBMITTER: Qian H 

PROVIDER: S-EPMC8716687 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature