The Role of Malnutrition and Muscle Wasting in Advanced Lung Cancer.

ABSTRACT:

Purpose of review

Malnutrition, cancer cachexia, and sarcopenia often co-occur in patients with advanced cancer and are associated with poorer response to chemotherapy and reduced survival. Here, we evaluate the current literature regarding the role of nutrition and these associated conditions in patients with advanced lung cancer.

Recent findings

While rates of malnutrition are high, nutritional intervention studies have generally been limited by small sample sizes. Novel strategies such as home-based meal delivery may have promise. While no therapy is approved for cancer cachexia, ghrelin agonists and other targeted therapies have yielded promising data in clinical trials. Recent data also suggest that obesity may improve immunotherapy responsiveness. Malnutrition and asso

SUBMITTER: Jain R 

PROVIDER: S-EPMC8717049 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature