Lateral Pelvic Lymph Node Dissection After Neoadjuvant Chemoradiotherapy in Patients With Rectal Cancer: A Single-Center Experience and Literature Review.

ABSTRACT:

Purpose

We aimed to evaluate the surgicopathological outcomes of lateral pelvic lymph node dissection (LPLD) and long-term oncological outcomes of selective LPLD after neoadjuvant chemoradiotherapy (nCRT) in patients with locally advanced rectal cancer and compare them to those of total mesorectal excision (TME) alone based on pretreatment magnetic resonance imaging (MRI).

Methods

We compared the TME-alone group (2001-2009, n=102) with the TME with LPLD group (2011-2016, n=69), both groups having lateral lymph nodes (LLNs) of ≥5 mm in short axis diameter. The surgicopathological outcomes were analyzed retrospectively. Oncological outcomes were analyzed using the Kaplan-Meier method.

Results

The rates of overall postoperative 30-day morbidity (42.0% vs. 26.5%, P=0.095)

SUBMITTER: Kim MC 

PROVIDER: S-EPMC8717070 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature