Risk of pacemaker implantation after radiotherapy for breast cancer: A study based on French nationwide health care database sample.

ABSTRACT:

Background

Among cardiac complications of breast cancer radiotherapy (BC RT), there are very limited data on arrhythmia and conduction disorders, in particular severe cases requiring permanent pacemaker implantation (PPMI). Therefore, this exploratory study aimed to evaluate the risk of PPMI for BC patients treated with RT, compared with the general population and with BC patients not treated with RT.

Methods

The study was performed on a 1/97 representative sample of the French health care database (EGB database). Adult women with a first BC treated with or without RT between 2008 and 2016 were included, followed until 2018, and de novo PPMI were identified. We compared the PPMI incidence in BC cohort relative to the general population with standardized incidence ratio (SIR)

SUBMITTER: Errahmani MY 

PROVIDER: S-EPMC8717594 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature