Association of systemic inflammation with survival in patients with cancer cachexia: results from a multicentre cohort study.

ABSTRACT:

Background

Although systemic inflammation is an important feature of the cancer cachexia, studies on the association between systemic inflammation and prognostic of cancer cachexia are limited. The objective of this study is to evaluate whether the neutrophil-to-lymphocyte ratio (NLR) is associated with outcome and quality of life for patients with cancer cachexia and investigated any interaction between NLR and the clinical parameters.

Methods

This is a multicentre cohort study of 2612 cancer patients suffering from cachexia diagnosed between June 2012 and December 2019. The main parameters measured were overall survival (OS) time and all-cause mortality. The association between NLR and all-cause mortality was evaluated using hazard ratios (HRs) and the restricted cubic spl

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC8718079 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature