Targeting memory T cell metabolism to improve immunity.
Ontology highlight
ABSTRACT:
SUBMITTER: Corrado M
PROVIDER: S-EPMC8718135 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Publications
Targeting memory T cell metabolism to improve immunity.
Corrado Mauro M Pearce Erika L EL
The Journal of clinical investigation 20220101 1
Vaccination affords protection from disease by activating pathogen-specific immune cells and facilitating the development of persistent immunologic memory toward the vaccine-specific pathogen. Current vaccine regimens are often based on the efficiency of the acute immune response, and not necessarily on the generation of memory cells, in part because the mechanisms underlying the development of efficient immune memory remain incompletely understood. This Review describes recent advances in defin ...[more]
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