Outcomes and Incidence of PF-ILD According to Different Definitions in a Real-World Setting.

ABSTRACT: Background: Almost one-third of fibrosing ILD (fILDs) have a clinical disease behavior similar to IPF, demonstrating a progressive phenotype (PF-ILD). However, there are no globally accepted criteria on the definition of a progressive phenotype in non-IPF fILD yet. Four different definitions have been used; however, no internationally accepted definition currently exists. Research Question: To compare the clinical and functional characteristics of progressive fILD according to the currently available definitions. Study design and methods: Cases of fILD were identified retrospectively from the database of the tertiary referral center for ILD in Heidelberg. Lung function, clinical signs of progression, and radiological changes were evaluated. Patients with fILD were cons

SUBMITTER: Torrisi SE 

PROVIDER: S-EPMC8718675 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature