Case Report and Systematic Review: Sarcomatoid Parathyroid Carcinoma-A Rare, Highly Malignant Subtype.

ABSTRACT:

Background

Parathyroid carcinoma (PC) is a rare malignancy, the incidence of which is less than 1/1 million per year. Sarcomatoid parathyroid carcinoma (SaPC) is an extremely peculiar subtype; only three cases have been reported internationally. It consists of both malignant epithelial components and sarcomatoid components (mesenchymal origin) simultaneously. This "confusing" cancer exhibits higher invasiveness, and traditional surgery does not appear to achieve the expectation, which differs significantly from that of general PC.

Objective

To characterize the clinicopathologic features of SaPC and explore similarities and differences between SaPC and general PC.

Materials and methods

We collected clinical data of SaPC cases from our center and literature. The SaPC ca

SUBMITTER: Yu Y 

PROVIDER: S-EPMC8719313 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature