Why should obese youth be prioritized in COVID-19 vaccination programs? A nationwide retrospective study.

ABSTRACT:

Background

The dominant effect of age on COVID-19 mortality obscures the impact of other risk factors. Although the elderly is at a greater risk of severe disease and death due to COVID-19, the interaction of obesity and age was not carefully assessed. This analysis is especially critical for prioritizing groups to receive COVID-19 vaccination.

Methods

Starting with 1,120,767 unvaccinated individuals registered in a Brazilian surveillance system, we selected 313,898 hospitalized COVID-19 patients aged 20 to 89 who had a BMI ≥ 25 kg/m² and cardiovascular diseases (CVD) or diabetes, as well as individuals with no risk factors associated with severe COVID-19. Patient data were stratified by age, obesity, BMI, and comorbidities, and subsequently, subjected to crude an

SUBMITTER: Discacciati MG 

PROVIDER: S-EPMC8720147 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature