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ABSTRACT: Introduction
Exposure to noise might influence risk of Alzheimer's disease (AD) dementia.Methods
Participants of the Chicago Health and Aging Project (≥65 years) underwent triennial cognitive assessments. For the 5 years preceding each assessment, we estimated 5227 participants' residential level of noise from the community using a spatial prediction model, and estimated associations of noise level with prevalent mild cognitive impairment (MCI) and AD, cognitive performance, and rate of cognitive decline.Results
Among these participants, an increment of 10 A-weighted decibels (dBA) in noise corresponded to 36% and 29% higher odds of prevalent MCI (odds ratio [OR] = 1.36; 95% confidence interval [CI], 1.15 to 1.62) and AD (OR = 1.29, 95% CI, 1.08 to 1.55). Noise leve
SUBMITTER: Weuve J
PROVIDER: S-EPMC8720224 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature