Exercise-Induced Ventricular Ectopy and Cardiovascular Mortality in Asymptomatic Individuals.

ABSTRACT:

Background

The prognosis of exercise-induced premature ventricular contractions (PVCs) in asymptomatic individuals is unclear.

Objectives

This study sought to investigate whether high-grade PVCs during stress testing predict mortality in asymptomatic individuals.

Methods

A cohort of 5,486 asymptomatic individuals who took part in the Lipid Research Clinics prospective cohort had baseline interview, physical examination, blood tests, and underwent Bruce protocol treadmill testing. Adjusted Cox survival models evaluated the association of exercise-induced high-grade PVCs (defined as either frequent (>10 per minute), multifocal, R-on-T type, or ≥2 PVCs in a row) with all-cause and cardiovascular mortality.

Results

Mean baseline age was 45.4 ± 10.8 years; 42% were

SUBMITTER: Refaat MM 

PROVIDER: S-EPMC8720278 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature