Undetectable Production of the VIM-1 Carbapenemase in an Atlantibacter hermannii Clinical Isolate.

ABSTRACT: The differential expression of VIM-1 in Atlantibacter hermannii WEB-2 and Enterobacter hormaechei ssp. hoffmannii WEB-1 clinical isolates from a rectal swab of a hospitalized patient in France was investigated. A. hermannii WEB-2 was resistant to all β-lactams except carbapenems. It produced ESBL SHV-12, but the Carba NP test failed to detect any carbapenemase activity despite the production of VIM-1. Conversely, E. hormaechei WEB-1, previously recovered from the same patient, was positive for the detection of carbapenemase activity. The bla _VIM-1 gene was located on a plasmid and embedded within class 1 integron. Both plasmids were of the same IncA incompatibility group and conferred the same resistance pattern when electroporated in

SUBMITTER: Girlich D 

PROVIDER: S-EPMC8721206 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature