Employment status at transplant influences ethnic disparities in outcomes after deceased donor kidney transplantation.

ABSTRACT:

Background

African American (AA) recipients of deceased-donor (DD) kidney transplants (KT) have shorter allograft survival than recipients of other ethnic groups. Reasons for this disparity encompass complex interactions between donors and recipients characteristics.

Methods

Outcomes from 3872 AA and 19,719 European American (EA) DDs who had one kidney transplanted in an AA recipient and one in an EA recipient were analyzed. Four donor/recipient pair groups (DRP) were studied, AA/AA, AA/EA, EA/AA, and EA/EA. Survival random forests and Cox proportional hazard models were fitted to rank and evaluate modifying effects of DRP on variables associated with allograft survival. These analyses sought to identify factors contributing to the observed disparities in transplant outcomes

SUBMITTER: Divers J 

PROVIDER: S-EPMC8722061 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature