Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study.

ABSTRACT:

Background

Mechanical power is a composite variable for energy transmitted to the respiratory system over time that may better capture risk for ventilator-induced lung injury than individual ventilator management components. We sought to evaluate if mechanical ventilation management with a high mechanical power is associated with fewer ventilator-free days (VFD) in children with pediatric acute respiratory distress syndrome (PARDS).

Methods

Retrospective analysis of a prospective observational international cohort study.

Results

There were 306 children from 55 pediatric intensive care units included. High mechanical power was associated with younger age, higher oxygenation index, a comorbid condition of bronchopulmonary dysplasia, higher tidal volume, higher delta pre

SUBMITTER: Bhalla AK 

PROVIDER: S-EPMC8722295 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature