PurgeR: inbreeding and purging in pedigreed populations.

ABSTRACT:

Summary

Inbreeding depression and genetic purging are important processes shaping the survivability and evolution of small populations. However, detecting purging is challenging in practice, in part because there are limited tools dedicated to it. I present a new R package to assist population analyses on detection and quantification of the inbreeding depression and genetic purging of biological fitness in pedigreed populations. It includes a collection of methods to estimate different measurements of inbreeding (Wright's, partial and ancestral inbreeding coefficients) as well as purging parameters (purged inbreeding, and opportunity of purging coefficients). Additional functions are also included to estimate population parameters, allowing to contextualize inbreeding and purging t

SUBMITTER: Lopez-Cortegano E 

PROVIDER: S-EPMC8723146 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature