Investigating the histological and structural properties of tendon gel as an artificial biomaterial using the film model method in rabbits.

ABSTRACT:

Purpose

This study aimed to evaluate the properties of tendon gel by investigating the histological and structural differences among tendon gels under different preservation periods using a rabbit model.

Methods

Forty mature female rabbits were divided into four groups, each containing ten rabbits, on the basis of in-vivo preservation periods of tendon gels (3, 5, 10, and 15 days). We created the Achilles tendon rupture models using the film model method to obtain tendon gels. Tensile stress was applied to the tendon gel to promote maturation. Histological and structural evaluations of the tendon gel were performed before and after applying the tensile force, and the results obtained from the four groups were compared.

Results

Although the day-3 and day-5 tendon gels

SUBMITTER: Shimozaki K 

PROVIDER: S-EPMC8724385 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature