The associations between orthostatic blood pressure changes and extracellular volume in hemodialysis patients.

ABSTRACT:

Introduction

Extracellular volume (ECV) predicts mortality in hemodialysis patients, but it is difficult to assess clinically. Peridialytic blood pressure (BP) measurements can help ECV assessment. Orthostatic BP is routinely measured clinically, but its association with ECV is unknown.

Methods

In a cohort of hypertensive hemodialysis patients, we measured posthemodialysis ECV/weight with bioimpedance spectroscopy and analyzed its association with post-HD orthostatic BP measurements obtained during routine care. Using linear and logistic regression, the primary outcomes were orthostatic BP change and orthostatic hypotension (OH) defined by systolic BP decrease of at least 20 mmHg or diastolic decrease of at least 10 mmHg. Model 1 controlled for sex, age, and diabetes. Model

SUBMITTER: Jeon-Slaughter H 

PROVIDER: S-EPMC8724409 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature