Invasive pulmonary aspergillosis among intubated patients with SARS-CoV-2 or influenza pneumonia: a European multicenter comparative cohort study.

ABSTRACT:

Background

Recent multicenter studies identified COVID-19 as a risk factor for invasive pulmonary aspergillosis (IPA). However, no large multicenter study has compared the incidence of IPA between COVID-19 and influenza patients.

Objectives

To determine the incidence of putative IPA in critically ill SARS-CoV-2 patients, compared with influenza patients.

Methods

This study was a planned ancillary analysis of the coVAPid multicenter retrospective European cohort. Consecutive adult patients requiring invasive mechanical ventilation for > 48 h for SARS-CoV-2 pneumonia or influenza pneumonia were included. The 28-day cumulative incidence of putative IPA, based on Blot definition, was the primary outcome. IPA incidence was estimated using the Kalbfleisch and Prentice metho

SUBMITTER: Rouze A 

PROVIDER: S-EPMC8724752 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature