Dataset Information
Efficacy of the bivalent HPV vaccine against HPV 16/18-associated precancer: long-term follow-up results from the Costa Rica Vaccine Trial.
Ontology highlight
ABSTRACT:
SUBMITTER: Porras C
PROVIDER: S-EPMC8724969 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
Efficacy of the bivalent HPV vaccine against HPV 16/18-associated precancer: long-term follow-up results from the Costa Rica Vaccine Trial.
The Lancet. Oncology 20201201 12
<h4>Background</h4>Oncogenic human papillomavirus (HPV) infections cause most cases of cervical cancer. Here, we report long-term follow-up results for the Costa Rica Vaccine Trial (publicly funded and initiated before licensure of the HPV vaccines), with the aim of assessing the efficacy of the bivalent HPV vaccine for preventing HPV 16/18-associated cervical intraepithelial neoplasia grade 2 or worse (CIN2+).<h4>Methods</h4>Women aged 18-25 years were enrolled in a randomised, double-blind, co ...[more]