The 2017 Dengue virus 1 outbreak in northern Vietnam was caused by a locally circulating virus group.

ABSTRACT:

Background

Dengue virus (DENV) is a member of insect vector-borne viruses, and it causes dengue fever. Southeast Asia is the epi-center of dengue fever in the world. The characterization of the virus is essential to identify the transmission and evolution of DENV.

Objectives

In 2017, there was an outbreak of Dengue virus type 1 (DENV1) in northern Vietnam and the neighboring countries. To identify the genetic character of the outbreak virus in the area, we conducted whole-genome sequencing analysis on the samples positive for the DENV1 along with real-time PCR.

Study design

In total, 1026 blood samples were collected from patients with suspected dengue fever in Ha Nam and Hai Duong province, nearby areas of the capital of Vietnam. After screening by real-time PCR, 40

SUBMITTER: Takemura T 

PROVIDER: S-EPMC8725327 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature