Exploration of a new hepatitis a surveillance system in Beijing, China: based on molecular epidemiology.

ABSTRACT:

Background

The incidence of hepatitis A virus (HAV) infection is low in Beijing, China, but the risk of outbreaks still exists. It is difficult to identify possible sources of infection among sporadic cases based on a routine surveillance system. Therefore, a more effective surveillance system needs to be established.

Methods

The epidemiological data of hepatitis A were obtained from a routine surveillance system. Patients with HAV confirmed at the local hospitals were asked to complete a questionnaire that included additional case information and possible sources of infection. Serum and fecal specimens were also collected for testing HAV RNA by polymerase chain reaction. In addition, the 321-nucleotide segment of the VP1/2A junction region was sequenced to determine the HAV

SUBMITTER: Wang H 

PROVIDER: S-EPMC8725380 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature