Immune function in childhood cancer survivors: a Children's Oncology Group review.

ABSTRACT: Childhood cancer and its treatment often impact the haematopoietic and lymphatic systems, with immunological consequences. Immunological assessments are not routinely included in surveillance guidelines for most survivors of childhood cancer, although a robust body of literature describes immunological outcomes, testing recommendations, and revaccination guidelines after allogeneic haematopoietic cell transplantation. Survivorship care providers might not fully consider the impaired recovery of a child's immune system after cancer treatment if the child has not undergone haematopoietic cell transplantation. We did a scoping review to collate the existing literature describing immune function after childhood cancer therapy, including both standard-dose chemotherapy and high-dose chemotherap

SUBMITTER: Guilcher GMT 

PROVIDER: S-EPMC8725381 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature