Evaluation of the current guidelines for antibacterial therapy strategies in patients with cirrhosis or liver failure.

ABSTRACT:

Background

Bacterial infections are common complications in patients with cirrhosis or liver failure and are correlated with high mortality. Clinical practice guideline (CPG) is a reference used to help clinicians make decisions. This systematic appraisal aimed to evaluate the methodological quality and summarize the recommendations of reported CPGs in these patients.

Methods

We systematically searched CPGs published from 2008 to 2019. The methodological quality of the included CPGs was assessed using the AGREE II instrument. We extracted and compared recommendations for prophylactic and empirical treatment strategies.

Results

Fourteen CPGs with a median overall score of 56.3% were included. The highest domain score was Clarity of Presentation (domain 4, 85.4%), and t

SUBMITTER: Dong Y 

PROVIDER: S-EPMC8725452 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature