Human Borna disease virus 1 (BoDV-1) encephalitis cases in the north and east of Germany.

ABSTRACT: In 2021, three encephalitis cases due to the Borna disease virus 1 (BoDV-1) were diagnosed in the north and east of Germany. The patients were from the states of Thuringia, Saxony-Anhalt, and Lower Saxony. All were residents of known endemic areas for animal Borna disease but without prior diagnosed human cases. Except for one recently detected case in the state of Brandenburg, all >30 notified cases had occurred in, or were linked to, the southern state of Bavaria. Of the three detected cases described here, two infections were acute, while one infection was diagnosed retrospectively from archived brain autopsy tissue samples. One of the acute cases survived, but is permanently disabled. The cases were diagnosed by various techniques (serology, molecular assays, and immunohistology) follo

SUBMITTER: Frank C 

PROVIDER: S-EPMC8725967 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature