Zinc carnosine-based modified bismuth quadruple therapy vs standard triple therapy for Helicobacter pylori eradication: A randomized controlled study.

ABSTRACT:

Background

Helicobacter pylori (H. pylori) infection is a worldwide problem with increasing burden on the health sector due to its increasing rate of resistance. The conventional triple therapy (TT) is becoming obsolete with a high failure rate of eradication, necessitating the need for better alternatives or regimens.

Aim

To investigate H. pylori eradication rate of TT vs modified bismuth quadruple therapy.

Methods

Ninety-two patients with dyspepsia symptoms and positive ¹³C-urea breath test were randomly assigned to two groups. The first group (control group) was treated for 14 d using standard TT protocol: Esomeprazole (40 mg twice daily), amoxicillin (1 g twice daily) and clarithromycin (500 mg twice daily). On the other hand

SUBMITTER: Ibrahim N 

PROVIDER: S-EPMC8727261 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature