Laterality of motor symptom onset and facial expressivity in Parkinson disease using face digitization.

ABSTRACT: The onset of motor symptoms in Parkinson disease (PD) is typically unilateral. Previous work has suggested that laterality of motor symptoms may also influence non-motor symptoms including cognition and emotion perception. In line with hemispheric differences in emotion processing, we tested whether left side/right brain motor onset was associated with worse expression of facial affect when compared to right side/left brain motor onset. We evaluated movement changes associated with facial affect in 30 patients with idiopathic PD (15 left-sided motor onset, 15 right-sided motor onset) and 20 healthy controls. Participants were videotaped while posing three facial expressions: fear, anger, and happiness. Expressions were digitized and analyzed using software that extracted three variables: t

SUBMITTER: Ratajska AM 

PROVIDER: S-EPMC8727642 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature