Cohort profile: the Mancio Lima cohort study of urban malaria in Amazonian Brazil.

ABSTRACT:

Purpose

This population-based open cohort study aims to investigate biological and sociodemographic drivers of malaria transmission in the main urban hotspot of Amazonian Brazil.

Participants

Nearly 20% of the households in the northwestern town of Mâncio Lima were randomly selected and 2690 participants were enrolled since April 2018. Sociodemographic, housing quality, occupational, behavioural and morbidity information and travel histories were collected during consecutive study visits. Blood samples from participants>3 months old were used for malaria diagnosis and human genetic studies; samples from participants with laboratory-confirmed malaria have been cryopreserved for genetic and phenotypic characterisation of parasites. Serology was introduced in 2020 to measure th

SUBMITTER: Johansen IC 

PROVIDER: S-EPMC8727682 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature