The Human-Milk Oligosaccharide Profile of Lactating Women in Dhaka, Bangladesh.

ABSTRACT:

Background

Human-milk oligosaccharides (HMOs) are an abundant component of human milk that have health-related effects on breastfeeding infants. Since variation in HMO composition can be explained by maternal and environmental factors, understanding the diversity in HMOs across settings and identifying context-specific factors associated with HMO abundances is important.

Objectives

The aim was to describe the HMO profile of Bangladeshi women and to estimate the effect of maternal vitamin D supplementation on HMO composition.

Methods

In a cross-sectional analysis of data and samples from the Maternal Vitamin D for Infant Growth trial in Dhaka, Bangladesh (clinicaltrials.gov; NCT01924013), 192 participants were randomly selected including 96 from each of the placebo and

SUBMITTER: Pell LG 

PROVIDER: S-EPMC8728024 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature