JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles.

ABSTRACT: JASPAR (http://jaspar.genereg.net/) is an open-access database containing manually curated, non-redundant transcription factor (TF) binding profiles for TFs across six taxonomic groups. In this 9th release, we expanded the CORE collection with 341 new profiles (148 for plants, 101 for vertebrates, 85 for urochordates, and 7 for insects), which corresponds to a 19% expansion over the previous release. We added 298 new profiles to the Unvalidated collection when no orthogonal evidence was found in the literature. All the profiles were clustered to provide familial binding profiles for each taxonomic group. Moreover, we revised the structural classification of DNA binding domains to consider plant-specific TFs. This release introduces word clouds to represent the scientific knowledge associat

SUBMITTER: Castro-Mondragon JA 

PROVIDER: S-EPMC8728201 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature