Dataset Information

The IntAct database: efficient access to fine-grained molecular interaction data.

ABSTRACT: The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions. As of August 2021, IntAct provides more than one million binary interactions, curated by twelve global partners of the International Molecular Exchange consortium, for which the IntAct database provides a shared curation and dissemination platform. The IMEx curation policy has always emphasised a fine-grained data and curation model, aiming to capture the relevant experimental detail essential for the interpretation of the provided molecular interaction data. Here, we present recent curation focus and progress, as well as a completely redeveloped website which presents IntAct data in a much more user-friendly and detailed way.

SUBMITTER: Del Toro N

PROVIDER: S-EPMC8728211 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature

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The IntAct database: efficient access to fine-grained molecular interaction data.

Del Toro Noemi N Shrivastava Anjali A Ragueneau Eliot E Meldal Birgit B Combe Colin C Barrera Elisabet E Perfetto Livia L How Karyn K Ratan Prashansa P Shirodkar Gautam G Lu Odilia O Mészáros Bálint B Watkins Xavier X Pundir Sangya S Licata Luana L Iannuccelli Marta M Pellegrini Matteo M Martin Maria Jesus MJ Panni Simona S Duesbury Margaret M Vallet Sylvain D SD Rappsilber Juri J Ricard-Blum Sylvie S Cesareni Gianni G Salwinski Lukasz L Orchard Sandra S Porras Pablo P Panneerselvam Kalpana K Hermjakob Henning H

Nucleic acids research 20220101 D1

The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions. As of August 2021, IntAct provides more than one million binary interactions, curated by twelve global partners of the International Molecular Exchange consortium, for which the IntAct database provides a shared curation and dissemination platform. The IMEx curation policy has always emphasised a fine-gr ...[more]

PMID: 34761267

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Project description:ObjectiveFine-grained classification of historical traditional villages plays a crucial role in guiding the future development and construction of urban and rural areas. This study aims to propose a new dataset for fine-grained classification of traditional villages and to propose an efficient progressive attention network for the problem of low accuracy and efficiency of fine-grained traditional historical village classification.Methods and resultsFirstly, in order to further study the long-standing problem of fine-grained classification of traditional villages, a new fine-grained classification dataset of traditional villages containing 4,400 images, referred to as PVCD, is proposed by crawling and hand-arranging. Secondly, a new Progressive Attention Module, abbreviated as PAM, is also proposed. PAM engages in attentional modeling of prominent spatial features within the spatial dimension, subsequently applying attentional modeling to channel features beneath the identified salient spatial features. This process involves salient spatial feature attention modeling of prominent channel features within the dimension to extract discriminative information for fine-grained classification, thereby enhancing the performance of classifying traditional villages with precision. Finally, a new knowledge distillation strategy of softened alignment distillation, or SAD for short, is proposed, which simply and efficiently transfers the knowledge of softened category probability distributions through. Notably, based on the above proposed PAM, the lightweight EPANet-Student and the heavyweight EPANet-Teacher are proposed. In addition, the heavyweight EPANet-Teacher transfers the knowledge of fine-grained categorization of traditional villages to the lightweight EPANet-Student through the proposed SAD, abbreviated as EPANet-KD. The experimental results show that the proposed EPANet-Teacher achieves state-of-the-art performance with an accuracy of 67.27%, and the proposed EPANet-KD achieves comparable performance to the proposed EPANet-Teacher with 3.32M parameters and 0.42G computation.ConclusionThe proposed EPANet-KD maintains a good balance of accuracy and efficiency in the fine-grained classification of traditional villages, considerably promoting the research on the fine-grained classification of traditional villages. In addition, it facilitates the digital preservation and development of traditional villages. All datasets, codes and benchmarking results are publicly available for the promotion of this research area. https://github.com/Jack13026212687/EPANet-KD.

Dataset Information

The IntAct database: efficient access to fine-grained molecular interaction data.

Publications

The IntAct database: efficient access to fine-grained molecular interaction data.

Similar Datasets

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